One-Step Suicide Substrate Inactivation Kinetics of a Ping-Pong Reaction with One Substrate Undergoing Disproportionation: A Theoretical Approach with Approximate Solutions

The kinetics of succinyl coenzyme A synthetase from Escherichia coli. A reaction with a covalent enzyme-substrate intermediate not exhibiting "ping-pong" kinetics.

Succinyl coenzyme A synthetase from Escherichia coli does not exhibit a steady state kinetic pattern indicative of “ping-pong” kinetics, despite the fact that catalytic participation of a phosphorylated enzyme covalent intermediate has been established. Instead, kineti.c patterns are consistent with the sequential addition of all substrates, to form a quaternary complex, before the release of a...

Derivation of rate equations for multisite ping-pong mechanisms with ping-pong reactions at one or more sites.

It has become clear as the result of the pioneering studies of Northrop on transcarboxylase (l), and the later studies in Lardy’s (2) and Utter’s (3) laboratories on pyruvate carboxylase that biotin-containing enzymes have two-site ping-pong mechanisms in which biotin is carboxylated at one site, and in turn carboxylates a substrate at the second site. The rate equations for such mechanisms hav...

single-step synthesis of multi-component spirobarbiturates using ionic liquids and synthesis of substituted pyridine filled with catalysts supported on solid substrate

in this thesis, a better reaction conditions for the synthesis of spirobarbiturates catalyzed by task-specific ionic liquid (2-hydroxy-n-(2-hydroxyethyl)-n,n-dimethylethanaminium formate), calcium hypochlorite ca(ocl)2 or n-bromosuccinimide (nbs) in the presence of water at room temperature by ultrasonic technique is provided. the design and synthesis of spirocycles is a challenging task becaus...

Analysis of the Ping-Pong Ball Gun-Theoretical & Computational Approach

Tree Automata with One Memory, Set Constraints, and Ping-Pong Protocols